1006 IMMUNE RECONSTITUTION IN PRIMARY IMMUNODEFICIENCIES BY INTERLEUKIN-2 (IL-2)
نویسندگان
چکیده
منابع مشابه
Functional Immune Reconstitution by Interleukin-2 Adjunctive Therapy for HIV/Mycobacterial Co-infection
been reported to be seropositive for CHIKV (2,6–8). These results indicate that CHIKV infects long-tailed macaques in Malaysia, but seroprevalence rates are low, and there is little evidence of viremia, except at the 1 specific site in Kuala Lipis. Although experimental infection of long-tailed macaques resulted in detectable CHIKV an-tigen in macrophages for >3 months, infectious CHIKV is not ...
متن کاملImmune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2.
Natural killer (NK) cells are believed to play a role in human immunodeficiency virus type 1 (HIV-1) disease progression, and NK cell levels are reduced in individuals with chronic HIV-1 infection. Interleukin (IL)-2 therapy results in an expansion of CD4(+) T cells as well as NK cells; however, little is known about the detailed effects of IL-2 therapy on NK cells in HIV-1 infection in general...
متن کاملQualitative Immune Modulation by Interleukin-2 (IL-2) Adjuvant Therapy in Immunological Non Responder HIV-Infected Patients
BACKGROUND Treatment of HIV-infected patients with interleukin-2 (IL-2) produces significant increases in CD4 T cell counts; however an associated qualitative improvement in cells function has yet to be conclusively demonstrated. By measuring mycobacterial killing activity, we evaluated IL-2-mediated functional immune enhancement ex vivo in immunological non-responders (INRs). METHODS AND FIN...
متن کاملInterleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
We demonstrate that purified interleukin 2 (IL-2) can directly upregulate IL-2 receptor expression on phytohemagglutinin-activated T lymphocytes maintained in culture until IL-2 receptor expression had markedly declined. The IL-2-induced increase in IL-2 receptor number is maximal within 12 hr, requires new RNA and protein synthesis, and is mediated by an interaction of ligand with the high-aff...
متن کاملIL 6 ( interleukin 6 ( interferon beta 2 ) )
Note: G/C polymorphism at nucleotide -174 (promoter region) Breast cancer prognosis differs between populations. Despite its lower incidence in Blacks when compared to Caucasians, mortality among the former is higher. Genetic factors involved in the molecular pathways regulating tumor development have been adduced to explain these differences, and it has been suggested that the IL-6 gene is a s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-01036